Personalized Molecular Therapy

Personalized molecular therapy is a contemporary field of medicine whose primary goal is to target the molecular mechanisms involved in disease pathogenesis and development. Nowadays, advanced genomic and molecular technologies are operated to discover the specific molecular signatures of patients responsible for their diseases. This approach significantly improves the quality and efficacy of treatment, particularly […]

Personalized Cell Therapy

Personalized cell therapy is a modern treatment that uses the patient’s viable cells or grafts to regenerate damaged organs. A personalized cell therapy cycle consists of I) identifying the most appropriate cell type based on the type of disease, stage, etc., II) isolating and culturing the cells, and III) infusing the cells into the patient. […]

Personalized Reproductive Medicine

Personalized reproductive medicine is a modern field of individualized medicine that deals with diseases of the reproductive system and infertility. Other objectives of this field include the prevention of infertility and subsequent treatment of reproductive disorders. Many years of research into the human genome and genetics have led us to several vital variations and mutations […]

Personalized Cancer Medicine

Personalized cancer medicine refers to a novel approach to personalized medicine based on an individual’s genome and biological processes. Several investigations have confirmed that specific genes largely control therapeutic outcome in cancer patients and that mutations directly control all stages of cancer development, progression, and response. In personalized cancer medicine, we seek to discover all […]

Base Editing: A Strong Contender in Cell and Gene Therapy

gen-therapy

Base editors, DNA double-strand break (DSB)-independent genome modification agents, have been recognized alongside prime editors as key technologies to watch this year,1 and advances to date have been encouraging. Although these technologies have yet to enter the clinic, the first candidate therapy received investigational new drug approval from the U.S. Food and Drug Administration in 2021—less […]

Enzyme that Promotes Diet-Induced Obesity Could Point to Inhibitor Therapy

highfat-diet

High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in Obesity. The researchers, headed by a New York University Grossman School of Medicine team, suggest that their findings could point to potential new strategies for treating obesity. […]

Lab-made sperm’ fertility hope

fertilityassaymale

Scientists have proved for the first time that sperm grown from embryonic stem cells can be used to produce offspring. The discovery in mice could ultimately help couples affected by male fertility problems to conceive. And by understanding embryo developmental processes better, a host of other diseases might be treated using stem cells, they say. […]

ISCA International Summerschool (COLOGNE, JULY 8-10, 2019)

Applying Stem Cells in Personalized Medicine Download Brochure Recent development in stem cell technologies revealed that human stem cell can be used to test how diseased cells respond to drugs. This success highlights a pathway toward faster, cheaper and more difficult drug development for some genetic illnesses, as well as the ability to pre-test a […]