Personalized cell therapy is a modern treatment that uses the patient’s viable cells or grafts to regenerate damaged organs. A personalized cell therapy cycle consists of I) identifying the most appropriate cell type based on the type of disease, stage, etc., II) isolating and culturing the cells, and III) infusing the cells into the patient. To date, various types of human cells have been approved. Stem cells refer to a population of somatic cells that have the potential to generate mature types of cells. These cells play a central role in organ development, regeneration, and hemostasis from embryonic to adulthood. Using a patient’s own stem cells (autologous stem cell transplantation) is now emerging as a cutting-edge method for treating disease. Various analyzes have shown that this approach is a safe therapy and, in particular, supports the regeneration of degenerated tissue.
The use of immune cells for immune cell therapy is also cited as a valuable approach for treating different diseases such as cancer, rheumatological and immunological disorders. For example, parental lymphocytes, especially T cells and natural killer (NK) cells, are the immune cell types with the innate potential to destroy malignant tumor cells and are widely employed for personalized cancer therapy. In addition, regulatory T cells (T-reg), via inducing autotolerance by activating suppressor mechanisms, are a suitable option for personalized immunotherapy in rheumatic and immunological diseases.
